In the midst of central London, a successful Indian restaurant called 'Gaylord' is run by a Londoner of Indian origin called Pinu (Vinay Pathak). A well off businessman, Pinu however, is a very insecure and under-confident man, who views his own life as a string of tragicomic moments. Ever since his parents died in a plane crash, Pinu has lived with his quirky Gujarati foster family …there's Jaisukh Kaka, his wife Kanta Kaki and Rajat, their only son. A simple soul at heart, Pinu has many complexes - a special one being that he is a virgin and has experienced no intimacy with a woman. To top that, his biggest fear is to be laughed at by people… an ever-repeating phenomenon with him. Pinu is quite an introvert and has no real friends…the closest he has ever gotten to a friendship is with his foster brother Rajat, who is quite a contrast to his own personality. Rajat is a well-built and handsome man with a casual air about him; he is also the lead singer of a rock band. Rajat is very fond of Pinu, though is often a source of annoyance to him as he finds Pinu really funny.
After a failed and humiliating experience when Pinu went to India to have an arranged marriage to a traditional girl who finally dumped him at the altar and eloped with her lover, Pinu is broken and disheartened…traumatized to have been the laughing stock of the evening. He returns to London and pretends to his staff at the restaurant that his marriage went well, except that his bride is yet to join him as she is stuck in India due to Visa issues. Hiding behind his lie, Pinu is becoming a pretty depressed guy…lonely, bored and bitter. One day, a young Indian fellow called Kamles comes to his restaurant and asks for a job as a stand-up comedian. Quite thrown off, Pinu initially refuses but finally lets him join as a cook, who also does a stand-up act in the evenings. On the same day, he hires a new cashier - Renu (Gul Panag), a young art student from India, who has a passion for caricatures. Life changes dramatically for Pinu as Gaylord begins to transform… Renu works on the look of the place, makes cheerful caricatures for customers while Kamles is a fabulous cook with a great talent for making people laugh in his acts and soon the restaurant is more happening and the business is much better. But the greatest difference they bring to his life is friendship. There is a visible difference in Pinu's personality now, as he lets himself hang out a bit with them.