In his decade-spanning career, Rampal has won numerous awards and nominations. He has won the National Film Award for Best Supporting Actor and the Filmfare Award for Best Supporting Actor for Rock On!!. He was voted as the most desirable man in the Times Most Desirable Men 2012 online polls conducted by the Indiatimes Group.
Rampal established his production company Chasing Ganesha Films. He became a film producer with I See You (2006) under his banner and played the lead role. Outside of acting, Rampal has been involved in other business ventures. He has launched Lost Festival through association with Percept Limite